We Analyzed Osteo Bi Flex: 6 Things You Should Know (UPDATED)

Joint supplements can seem like a dime a dozen; try one and you’ve tried them all. But is there really such a thing as an effective joint supplement (that doesn’t break the bank)?

If you’ve ever used products for joint pain before, chances are you stumbled upon one that doesn’t work. Be it a joint supplement, a cream, or a patch.

Many of these products offer enticing promises, the customer reviews look mostly positive, but when it comes to getting actual results, you may not get quite what you expected.

The truth is, joint supplements are like any other supplement. There is a lot of trash out there. Finding a joint stack that actually works and is effective at reducing pain, improving flexibility, and supporting your long-term joint health can be a tricky task. But not an impossible one.

When it comes to finding an effective supplement (be it for joints or any other aspect of your health), the most important part is the formula. You will need to look closely at the ingredients that are being used, their dosages, and the research behind them.

A good-quality joint stack will have research-backed ingredients, in clinically effective doses, with a 100% transparent label so you see exactly what you’re paying for. Yes, it can be quite a hassle!

Fret not, though, as today we’ve done the legwork for you. We’ve inspected Osteo Bi Flex’s formula to see if it lives up to the hype, and if it’s a good value for money.

Is Osteo Bi Flex really that good for joint pain, flexibility, and strength? Is it all-natural? Is it safe?

To get an idea about what you can expect from Osteo Bi Flex, we will start by sharing a brief summary. Followed by our full, in-depth report.

Osteo Bi Flex Review at a Glance


  • Goods dosage of glucosamine
  • Contains a high-quality Boswellia serrata extract


  • Proprietary blends are a red flag
  • Glucosamine dosages over 500mg are unnecessary and waste capsule space
  • Oral collagen isn’t effective due to low absorption
  • Hyaluronic acid is an unproven ingredient for joint health
  • Ingredient blend is stuffed with filler ingredients – including the controversial titanium dioxide

Key Takeaway

Osteo Bi Flex looks like a decent joint supplement at first glance, but when you look closer, there are some serious issues. The positive is that Osteo Bi Flex contains a high amount of glucosamine dose, which is a good long-term joint health ingredient. However, doses higher than 500mg are unlikely to provide an extra benefit. That capsule space could’ve been used for other proven ingredients.

Most of the formula is hidden in a proprietary blend – not showing individual ingredient doses. Osteo Bi Flex could be 95% collagen for all we know, and that would be terrible as collagen is fairly ineffective when taken orally. Better joint stacks are available on the market for the price.

What do we recommend?

Click to See The Current 2 Best-Reviewed Joint Supplements

About Osteo Bi Flex

Osteo Bi Flex is a natural joint supplement made by a company of the same name. It is an extremely popular supplement in the U.K., U.S., Canada, and Australia among people suffering from chronic arthritis and joint stiffness, among other joint health issues.

The manufacturer says Osteo Bi Flex can give you these benefits:

  1. Improve joint mobility
  2. Ease joint pain
  3. Reduce stiffness and flare-ups

What makes Osteo Bi Flex stand out? Well, the manufacturers say it can help you as soon as within 7 days of taking it. This is not something you’ll see with every joint supplement, as most of them take at least a month or two to really show their effects.

This begs the question; are Osteo Bi Flex’s manufacturers being realistic and truthful with their claims? We’ll find out in detail how it works very soon!

Osteo Bi Flex Review: Key Facts

🙂BenefitsPromotes joint comfort, alleviates pain, soothes stiff joints
💊IngredientsBoswellia Serrata, Glucosamine, Chondroitin, MSM, Collagen, Boron, Hyaluronic Acid
🏢CompanyOsteo Bi-Flex
☑️AvailabilityAmazon.com, Walmart.com, CVS.com,…
💵Pricing$42.99/bottle (Amazon)

How to Use Osteo Bi Flex (Dosage Instructions)

The official directions for using Osteo Bi-Flex are to take 2 capsules per day with a meal. If you stick to these dosage recommendations, a 120-capsule bottle of Osteo Bi-Flex will last you a full month.

Osteo Bi Flex Ingredients

We can talk about the benefits all we want, but the most important question about Osteo Bi Flex Triple Strength reviews to answer is: are the ingredients effective?

Here is a list of Osteo Bi-Flex Triple Strength Ingredients:

  • Glucosamine HCl (1500mg)
  • Chondroitin/MSM Complex (1103mg)
  • Joint Shield 5-LOXIN ADVANCED (Boswellia serrata extract) (100mg)
  • Hyaluronic acid (unknown amount)
  • Chondroitin sulfate (unknown amount)
  • MSM (unknown amount)
  • Boron (unknown amount)
  • Collagen (unknown amount)
  • Boswellia serrata (unknown amount)

At first glance, Osteo Bi Flex’s formula looks decent. It contains some of the most researched natural joint supplements available, and their dosages are, for the most part, within optimal ranges. But there are also some issues with the ingredient profile – namely, the proprietary blend.

We’ll now inspect the ingredients in more detail, explaining how they work and what the evidence says. We have skipped past vitamin C and manganese as they are not really worth going over when talking about joint supplements.

Glucosamine HCl

Glucosamine is the main ingredient of many joint health formulas today. This makes complete sense when you realize that glucosamine is a core building block of proteins that your body uses to make connective tissues. Glucosamine is therefore naturally found in high amounts in your joint tissues; at least, that is in people with healthy joints.

Research suggests that glucosamine supplementation strengthens joints and lowers the risk of injury and joint pain.

Osteo Bi Flex contains a large 1500mg dose of Glucosamine HCl, which should be enough to provide all of its benefits.

Chondroitin/MSM Complex

Osteo Bi Flex doesn’t show us the exact amount of some ingredients inside. Instead, you can only see the combined amount of ingredients on the label. This is a red flag for us as it indicates that some ingredients might be underdosed.

Needless to say, in order for an ingredient to be effective, it needs to be dosed correctly. Due to the lack of transparency, the effectiveness of some of the following ingredients in Osteo Bi Flex is questionable.

Joint Shield 5-LOXIN ADVANCED (Boswellia serrata extract)

Boswellia comes in a high-quality patented form in Osteo Bi Flex. The active ingredients in Boswellia – boswellic acids – are known to reduce the harmful enyzme 5-LOX, which destroys your cartilage as you get older. By blocking this enzyme, Boswellia Serrata may help delay or even significantly diminish the gradual wear and tear of your joints – keeping them healthier for longer.

Chondroitin sulfate

Chondroitin is a molecular complex that absorbs water in your cartillage. As a result, it helps to lubricate your connective tissues, along with increasing your joint’s ability to absorb impacts and shocks.

The problem is that we can’t see this ingredient’s dosage on Osteo Bi Flex’s label, so it’s impossible to say how effective it is.

Hyaluronic acid

Hyaluronic acid is a natural compound found in the human body. You will see it being used in different products, including skincare and cosmetics to improve youthful skin appearance.

However, evidence on hyaluronic acid’s effectiveness in improving joint strength and flexibility is really thin. This ingredient could be taking up the most space in Osteo Bi Flex’s proprietary blend, which would be quite terrible.


MSM or Methylsulfonylmethane is a nutrient that helps your body create proteins, fluids, and other components integral to your joints. Our body needs MSM to make chondroitin, glucosamine, collagen, and other essential proteins in your connective tissues.

Sadly, this is another ingredient whose dosage is kept a secret in Osteo Bi Flex. Low doses aren’t shown to be effective.


Boron is not the most common ingredient in joint supplements. In fact, not all versions of Osteo Bi Flex contain boron; it’s omitted from the Triple Strength + Vitamin D version.

Regardless, the reason why boron isn’t so popular in joint formulas is that it’s not proven to significantly improve joint mobility, comfort, or any other aspect of joint health. What boron is known for is increasing bone density and improving testosterone levels in men.

While some animal studies suggest it may help to reduce joint aches and tissue breakdown, human evidence is almost nonexistent.


Now, collagen is something you can easily be tricked by. Collagen is a core building block of your connective tissues – without it, you would pretty much fall apart! However, it’s not great as a supplement – our digestive system doesn’t absorb it well. Most collagen that you consume through supplements tends to pass through the body without being utilized. Osteo Bi-Flex could be wasting a lot of money here depending on the percentage of the proprietary blend that collagen is taking up.

Our Commentary on Osteo Bi Flex’s Ingredient Profile

Osteo Bi Flex is not a bad joint supplement by any means. It is better than some other options on the market. However, is it the best we’ve seen? The answer is a definitive ‘no’.

The supplement has some excellent ingredients, which should help to keep your joints in a healthier place over the long-term, compared if you weren’t taking any supplement.

However, Osteo Bi Flex also contains ingredients that are not proven to work for joint health at all, and some of them even have hidden dosages on the label.

As a whole, Osteo Bi Flex is a mixed bag, with some good ingredients (some of which have their dosages hidden in a proprietary blend), and some ineffective ingredients. There’s simply too little transparency and too much junk going on for us to recommend it as one of the best joint supplements on the market.

Osteo Bi Flex Ease – Is it Better Than The Original?

Considering what we’ve seen with Osteo Bi Flex Triple Strength, you may wonder if the Osteo Bi Flex Ease version is a better alternative.

The answer is that Osteo Bi Flex Ease contains fewer ingredients than the original Osteo Bi Flex, and it has collagen instead of Glucosamine. As we’ve seen, glucosamine is an excellent joint health compound and is proven to have an effect on joints in most people with pain and stiffness. On the other hand, collagen is ineffective for the most part due to its low absorption.

Osteo Bi Flex Ease still gives us some Boswellia Serrata, but overall, the original Osteo Bi Flex Triple Strength is a better supplement by a distane.

Customer Reviews

Osteo Bi Flex reviews can easily be found on websites like Amazon. Reviews are generally positive, with one customer saying they feel less pain in their feet and knees when walking. Another mentioned reduced stiffness in their joints. Meanwhile, there are some users who describe the supplement as a “letdown.”

The U.S.-based company doesn’t have an official Better Business Bureau (BBB) rating. Osteo Bi-Flex capsules also aren’t approved by the FDA. But they are made in FDA-approved facilities.

Does Osteo Bi Flex Have Side Effects?

Some of the most questions you’ll see online being asked about the product include:

Is Osteo Bi Flex safe? Can it lead to side effects? Can Osteo Bi Flex cause kidney stones? Can Osteo Bi Flex cause joint pain? Can Osteo Bi Flex cause weight gain? Can Osteo Bi Flex cause heartburn?

The answer to all of these is probably not.

We don’t think Osteo Bi Flex will cause side effects in the majority of users. The ingredients in the supplement are common to joint supplements and have been tested in a variety of studies. None of the studies reported serious negative effects or risks from using any of the ingredients that are found in Osteo Bi Flex.

A big warning, however, is that we do not know the individual dosages of some ingredients in Osteo Bi Flex.

As such, side effects are always a possibility. If you experience any, discontinue use and seek medical attention as soon as possible.

*You should check with a qualified professional if you aren’t sure whether to take this product or not. Remember, our posts aren’t meant as advice – they’re for informational and entertainment purposes only!

Where to Buy?

Osteo Bi Flex can be bought on numerous websites online, including Amazon, Walmart, Walgreens, CVS, Vitamin Shoppe, and more. It is available not only in the USA but also around the world.

There are currently no official coupons or discounts for Osteo Bi Flex. That doesn’t mean that there are never any. Sometimes, such as during Black Friday, Osteo Bi Flex might be available for a discounted price.

Osteo Bi Flex vs Osteo Bi Flex Ease – Which is Better?

As we mentioned early on, you can find different versions of Osteo Bi Flex online and in stores. These include Triple Strength, Triple Strength with Magnesium, Triple Strength with Vitamin D, and Osteo Bi Flex Ease (or simply Joint Health Ease).

After Triple Strength, Ease is the most popular variation of Osteo Bi Flex.

So, what is different between the two versions of the same product – and which is better?

In a nutshell, Osteo Bi Flex Triple Strength contains more ingredients than Osteo Bi Flex Ease, along with using Glucosamine instead of Collagen that is in Ease.

So essentially, Ease is a stripped down Osteo Bi Flex Triple Health Formula. If you’ve read our full Osteo Bi-Flex review above, you’re aware that collagen is not a good substitute to Glucosamine! There are no credible human studies proving that subjects joint function and pain improved after using collagen. It simply doesn’t get absorbed well in our body; instead, you need to synthesize your own from compounds like Glucosamine and MSM!

Conversely, Glucosamine is a proven joint health ingredient; clinical data repeatedly shows that individuals’ joint flexibility and comfort improves within 28 days using a quality Glucosamine product.

While Osteo Bi Flex Ease still has some 5-LOXIN Advanced, the Triple Strength version is in our eyes the superior joint supplement, offering more value for your money.

The Bottom Line

Should you purchase and try Osteo Bi Flex? Is it worth the time and money?

While it has some positive things going for it, I say the answer is no. You can find more comprehensive and higher-quality joint stacks on the market today.

The inclusion of the proprietary blend and some untested, ineffective ingredients is where this supplement falls short for us.

Better and more transparent supplements for improving joint function, comfort, and mobility can be found elsewhere.

Not what you were looking for?

Click to See The Current 2 Best-Rated Joint Supplements

[Further Reading]:

1 thought on “We Analyzed Osteo Bi Flex: 6 Things You Should Know (UPDATED)”

  1. Bottom line is that all of you are out for money in the supplement industry and are by and large full of 💩.

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